- R&D
- Brighter future, by specialized research.
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WLHF-005(Fatdizol®)
Metabolic disease
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WLHF-005(Fatdizol®) is a new natural material that can help people with metabolic diseases such as obesity.
- Background
- The obesity rate in adults is steadily increasing, and one of three people was reported to obesity in 2016
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Obesity could cause vascular diseases such as high blood pressure, hyperlipidemia, and stroke, and various diseases such as diabetes, sleep apnea, and fatty liver.
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Skinny fat could look healthy on the outside. However, intra-abdominal fat accumulated obesity could be even more dangerous because it causes cardiovascular and cerebrovascular disease.
- Efficacy evaluation of WLHF-005(Fatdizol®)
- WLHF-005(Fatdizol®) effectively reduces body fat by inhibiting the accumulation of carbohydrates and fats, and by increasingthe metabolic rate to promote the decomposition of accumulated fat.
| Division | The inhibition of lipogenesis | Blocking carbohydrate absorption | Increasing basal metabolic rate | 비고 |
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| Fatdizol® |  |
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Korea |
| garcinia cambogia | |
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Imported | |
| wild mango seed extract | |
India | ||
| Xanthigen | |
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Spain | |
| Finger root | |
Indonesia | ||
| Pu'er tea | |
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China | |
| Green coffee beans extract | |
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France |
WLHF-005(Fatdizol®) suppresses fat synthesis by inhibiting the expression of various proteins involved in lipogenesis in adipose tissue.
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※ LPL hydrolyzes the triglycerides carried in chylomicrons and VLDL to fatty acids, which can be taken up by cells.
※ SREBP-1c regulates genes required for lipid production and its expression is regulated by insulin.
※ aP2 is thought to regulate fatty acid uptake, release, and storage in adipocytes
WLHF-005(Fatdizol®) increases energy expenditure by promoting thermogenesis.
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※ UCP2 has been proposed to regulate thermogenesis and energy expenditure in brown adipose tissue.